Depending on the route of administration, the Cmax will vary. Giving the same dose orally, intravenously, and via inhalation results in a different Cmax and Tmaxfor each.
|Inhalation Cmax||>||IV Cmax||>||Oral Cmax.|
|Oral Tmax||>||IV Tmax||>||Inhalation Tmax.|
Note that the AUC is unchanged.
When we look at giving a patient a dose of an actual drug, the formulation may already be chosen for us (dependent on the chemical properties of the drug). Infusing an IV drug over a different length of time, however, will affect the Cmax and Tmax in the same way as the route of administration. We will look at this effect later.